Linear mitochondrial DNA is rapidly degraded by components of the replication machinery

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery, Published online: 30 April 2018; doi:10.1038/s41467-018-04131-w

Damaged linearized mtDNA needs to be removed from the cell for mitochondrial genome stability. Here the authors shed light into the identity of the machinery responsible for rapidly degrading linearized DNA, implicating the role of mtDNA replication factors.

from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader https://ift.tt/2JCKpBE