Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation

Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation

Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation, Published online: 30 April 2018; doi:10.1038/s41467-018-04072-4

Non-coding RNAs have been shown to be key components in translational regulation. Here the authors characterize long nucleolus specific lncRNA termed LoNA, identified to play a role in protein biosynthesis by inhibiting rRNA production and ribosome biosynthesis in nucleoli.

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