GSE90929 Transcriptional changes in the primary somatosensory cortex upon sensory deprivation

Contributors : Koen Kole ; Yutaro Komuro ; Jan Provaznik ; Jelena Pistolic ; Vladimir Benes ; Paul Tiesinga ; Tansu Celikel
Series Type : Expression profiling by high throughput sequencing
Organism : Mus musculus

Experience-dependent plasticity (EDP) is essential for anatomical and functional maturation of sensory circuits during development and can be readily studied is the rodent barrel cortex. Using this model we aimed to uncover changes on the transcriptome level and applied RNA sequencing upon altered sensory experience in juvenile mice in a cortical column and layer specific manner. From column- and layer-specific barrel cortical tissue, high quality RNA was purified and sequenced. The current dataset entails an average of 50 million paired-end reads per sample, 75 base pairs in length.

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