Acetaminophen is one of the most widely used analgesic drugs, yet the exact mechanism of its analgesic effect remains largely unknown. Although originally thought to share similar mechanistic properties with cyclooxygenase (COX) inhibitors, acetaminophen is only weakly anti-inflammatory [1] and appears to inhibit prostaglandin synthesis centrally rather than peripherally, accounting for its antipyretic activity [2]. However, COX inhibition by acetaminophen may only occur under specific low peroxide conditions, likely explaining its known tissue selectivity [3].
from # All Medicine by Alexandros G. Sfakianakis via ola Kala on Inoreader http://ift.tt/2rpMyIi
via IFTTT
Παρασκευή 16 Ιουνίου 2017
Acetaminophen and ondansetron: The central serotonergic connection
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Recent research suggests that exercise stereotypes may influence physical activity through ego depletion and internalization mechanisms. The...
-
Publication date: Available online 16 June 2017 Source: Radiotherapy and Oncology Author(s): Mary McLay, Adrienne Stedford, Emily Yurkow...
-
Volume 10, Issue 2-3 , June - October 2016, Page ebi-ebi . from Med TandfOnline via Αλέξανδρος Σφακιανάκης on Inoreader http://ift.tt/2e...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου